Triamcinolone acetonide
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Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin conditions, reduce inflammation, and suppress the immune system. It is commonly marketed under brand names such as Kenalog and Nasacort.
Medical uses[edit | edit source]
Triamcinolone acetonide is used in the treatment of several conditions, including:
It is available in various forms, including topical creams, ointments, nasal sprays, and injectable solutions.
Mechanism of action[edit | edit source]
Triamcinolone acetonide works by inhibiting the release of substances in the body that cause inflammation. It binds to glucocorticoid receptors, leading to a decrease in the production of inflammatory mediators such as prostaglandins and leukotrienes.
Side effects[edit | edit source]
Common side effects of triamcinolone acetonide include:
- Skin irritation
- Dryness
- Redness
- Burning sensation
Long-term use can lead to more serious side effects such as:
Pharmacokinetics[edit | edit source]
Triamcinolone acetonide is metabolized in the liver and excreted primarily through the kidneys. The elimination half-life varies depending on the route of administration.
Contraindications[edit | edit source]
Triamcinolone acetonide should not be used in individuals with:
- Systemic fungal infections
- Known hypersensitivity to the drug
See also[edit | edit source]
References[edit | edit source]
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