Acid peptic diseases

Acid Peptic Diseases are a group of disorders that result from the damage to the gastrointestinal tract caused by gastric acid. These diseases include GERD, PUD, and ZES.

Overview

Acid peptic diseases are conditions that cause damage to the gastrointestinal tract due to the corrosive action of stomach acid. The most common acid peptic diseases are GERD, PUD, and ZES.

Causes

The primary cause of acid peptic diseases is the imbalance between the protective factors of the gastrointestinal tract and the corrosive action of gastric acid. Other factors that can contribute to the development of these diseases include H. pylori infection, use of NSAIDs, and excessive secretion of gastric acid due to a gastrin-secreting tumor.

Symptoms

The symptoms of acid peptic diseases can vary depending on the specific condition. However, common symptoms include heartburn, dyspepsia, nausea, and vomiting. In severe cases, these diseases can lead to complications such as gastrointestinal bleeding, perforation, and gastric outlet obstruction.

Diagnosis

Diagnosis of acid peptic diseases typically involves a combination of medical history, physical examination, and diagnostic tests such as endoscopy and biopsy. In some cases, additional tests such as barium swallow or esophageal manometry may be required.

Treatment

Treatment of acid peptic diseases primarily involves lifestyle modifications and medications to reduce the production of gastric acid. In some cases, surgery may be required to treat complications or if conservative treatment fails.

See Also

• GERD
• PUD
• ZES
• H. pylori
• NSAIDs
• gastrin-secreting tumor

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