(R)-2-Hydroxyglutarate

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Synonyms

(R)-2-Hydroxyglutarate, (2R)-2-Hydroxypentanedioic Acid, (R)-2-Hydroxyglutaric Acid, (R)-2HG, (R)-Hydroxyglutarate, D-2-HG, D-2-Hydroxyglutarate, D-2-Hydroxyglutarate, D-2HG, D2HG

Thesaurus

The R-enantiomer of alpha-hydroxyglutarate (2-HG) where the hydroxy group is attached to the right side of the asymmetric carbon furthest from the carbonyl. This isoform is the predominant form found in gliomas associated with the expression of isocitrate dehydrogenase (IDH) mutants. Therefore, measurement of the expression of the R-form may be correlated more closely with those diseases than measurement of total 2-HG. D-2-Hydroxyglutarate, Organic Chemical

NCI Thesaurus (external)

C120005.

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