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1,3 Diaxial interaction

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The steric intereaction between two methyl or larger groups attached at the 1 and 3 cis positions of cyclohexanes. The cyclohexane is in a higher energy state in the ring flip conformation that results in both 1 and 3 positions being axial due to steric strain between the 2 groups. This strain does not exist when hydrogens are bonded at these positions.

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