From Encyclopedia & World Directory
123i ibzm - a radiopharmaceutical containing the dopamine d2/d3 receptor agonist iodobenzamide (ibzm) labeled with the radionuclide iodine I 123 with dopamine receptor binding and radioisotopic activities. Upon administration, iodine I 123 iodobenzamide binds to dopamine d2/d3 receptors; subsequently, tissues expressing these receptors can be visualized using single photon emission computed tomography (spect). Dopamine receptors are a class of metabotropic g protein coupled receptors found in the central nervous system (cns) and neuroendocrine tumors such as pheochromocytoma and paraganglioma.
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