Minimization
A method of allocation used to provide comparison groups that are closely similar for several variables. The next participant is assessed with regard to several characteristics, and assigned to the treatment group that has so far had fewer such people assigned to it. It can be done with a component of randomization, where the chance of allocation to the group with fewer similar participants is less than one. Minimization is best performed centrally with the aid of a computer program to ensure concealment of allocation.
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