Trotter's syndrome
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Trotter's syndrome is a cluster of symptoms associated with certain types of advanced nasopharyngeal carcinoma. The cause of pain is the mandibular nerve of the foramen ovale, through which the tumor enters the calvarium.[1] Symptoms include the following:[2]
- Unilateral conductive deafness due to middle ear effusion
- Trigeminal neuralgia due to perineural spread
- Soft palate immobility
- Difficulty opening mouth
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Contributors: Prab R. Tumpati, MD