United Kingdom Model for End-Stage Liver Disease
The United Kingdom Model for End-Stage Liver Disease or UKELD is a medical scoring system used to predict the prognosis of patients with chronic liver disease. It is used in the United Kingdom to help determine the need for liver transplantation.[1] It was developed from the MELD score, incorporating the serum sodium level.[2]
Determination[edit | edit source]
The UKELD score is calculated from the patient's INR, serum creatinine, serum bilirubin and serum sodium, according to the formula:[3]
<math>(5.395 \times \ln INR) + (1.485 \times \ln creatinine) + (3.13 \times \ln bilirubin) - (81.565 \times \ln Na) + 435</math>
Interpretation[edit | edit source]
Higher UKELD scores equate to higher one-year mortality risk. A UKELD score of 49 indicates a 9% one-year risk of mortality, and is the minimum score required to be added to the liver transplant waiting list in the U.K.[1] A UKELD score of 60 indicates a 50% chance of one-year survival.[2]
History[edit | edit source]
The UKELD score was developed in 2008 to aid in the selection of patients for liver transplantation in the U.K.[4]
See also[edit | edit source]
- Model for End-Stage Liver Disease
- MELD-Plus
- Pediatric End-Stage Liver Disease
- Milan criteria
- Child-Pugh score
References[edit | edit source]
External links[edit | edit source]
- "UKELD calculator". NHS Blood and Transplant. Retrieved 2013-01-20. (Microsoft Excel file)
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Contributors: Prab R. Tumpati, MD
