Amyotrophic lateral sclerosis-parkinsonism/dementia complex 1
Other Names: Amyotrophic lateral sclerosis, Parkinsonism/Dementia complex of Guam; Guam disease A rare form of ALS that often runs in families is known as ALS-parkinsonism-dementia complex (ALS-PDC). This disorder is characterized by the signs and symptoms of ALS, in addition to a pattern of movement abnormalities known as parkinsonism, and a progressive loss of intellectual function (dementia). Signs of parkinsonism include unusually slow movements (bradykinesia), stiffness, and tremors. Affected members of the same family can have different combinations of signs and symptoms.
NIH genetic and rare disease info[edit source]
Amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 is a rare disease.
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