Automated insulin delivery system

Artificial Pancreas

Bio-artificial pancreas with Islet Sheet technology

This medical device related article is a stub.

An automated insulin delivery system, also known as an artificial pancreas or closed-loop insulin delivery system, is a medical device designed to automatically monitor and regulate blood glucose levels in individuals with diabetes mellitus. This system aims to mimic the glucose-regulating function of a healthy pancreas by delivering the appropriate amount of insulin in response to blood glucose levels.

Components

An automated insulin delivery system typically consists of the following components:

• Continuous glucose monitor (CGM): A device that continuously measures glucose levels in the interstitial fluid.
• Insulin pump: A device that delivers insulin through a catheter placed under the skin.
• Control algorithm: Software that calculates the required insulin dose based on CGM readings and other factors.

Function

The system works by continuously monitoring blood glucose levels using the CGM. The control algorithm processes this data and determines the appropriate insulin dose, which is then delivered by the insulin pump. This closed-loop system can adjust insulin delivery in real-time, helping to maintain blood glucose levels within a target range and reduce the risk of hyperglycemia and hypoglycemia.

Benefits

Automated insulin delivery systems offer several benefits, including:

• Improved blood glucose control
• Reduced risk of diabetes-related complications
• Increased convenience and quality of life for individuals with diabetes

Challenges

Despite their advantages, these systems also face challenges such as:

• High cost
• Technical issues with device accuracy and reliability
• Need for regular calibration and maintenance

Future Developments

Ongoing research aims to improve the accuracy, reliability, and affordability of automated insulin delivery systems. Advances in artificial intelligence and machine learning are expected to enhance the performance of control algorithms, making these systems more effective and user-friendly.

Related Pages

• Diabetes mellitus
• Insulin pump
• Continuous glucose monitor
• Hyperglycemia
• Hypoglycemia