Dexbrompheniramine maleate

From WikiMD's Food, Medicine & Wellness Encyclopedia

Dexbrompheniramine Maleate is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, watery eyes, itchy eyes/nose/throat/skin, cough, runny nose, and sneezing. It is also used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. Dexbrompheniramine helps control symptoms but does not treat the cause of the symptoms or speed recovery. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. This medication also blocks another natural substance in your body (acetylcholine).

Pharmacology[edit | edit source]

Dexbrompheniramine is a histamine H1 receptor antagonist. It competes with histamine for the normal post-synaptic H1 receptors on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract. This prevents histamine from having an effect on these cells, thereby preventing the symptoms associated with allergies and colds.

Side Effects[edit | edit source]

Common side effects of dexbrompheniramine include drowsiness, dizziness, headache, constipation, stomach upset, blurred vision, and dry mouth/nose/throat. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Interactions[edit | edit source]

Dexbrompheniramine can interact with a number of other medications, including monoamine oxidase inhibitors (MAOIs), alcohol, sedatives, tranquilizers, sleeping pills, muscle relaxants, antidepressants, and antihypertensive drugs. Always consult with a healthcare provider before starting or stopping any medication.

Precautions[edit | edit source]

Before taking dexbrompheniramine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD