Diflucortolone

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Diflucortolone.svg

Diflucortolone is a corticosteroid used in the treatment of various skin conditions. It is known for its anti-inflammatory, anti-pruritic, and vasoconstrictive properties. Diflucortolone is commonly used in the form of diflucortolone valerate, which is a more potent ester of the drug.

Medical Uses[edit | edit source]

Diflucortolone is primarily used to treat inflammatory skin disorders such as eczema, psoriasis, and dermatitis. It helps to reduce the symptoms of these conditions, including redness, swelling, and itching. The medication is typically applied topically in the form of a cream, ointment, or lotion.

Mechanism of Action[edit | edit source]

As a corticosteroid, diflucortolone works by inhibiting the release of substances in the body that cause inflammation. It reduces the activity of the immune system, thereby decreasing inflammation and the associated symptoms.

Side Effects[edit | edit source]

Common side effects of diflucortolone include skin irritation, dryness, and redness at the site of application. Prolonged use can lead to more serious side effects such as skin thinning, stretch marks, and systemic absorption leading to Cushing's syndrome.

Precautions[edit | edit source]

Patients using diflucortolone should follow their healthcare provider's instructions carefully. It is important to avoid using the medication on broken or infected skin unless directed by a healthcare provider. Long-term use should be monitored to prevent potential side effects.

Contraindications[edit | edit source]

Diflucortolone should not be used in individuals who are allergic to corticosteroids or any of the ingredients in the formulation. It is also contraindicated in patients with untreated bacterial, viral, or fungal skin infections.

Related Topics[edit | edit source]

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD