Furanylfentanyl

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Furanylfentanyl
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Furanylfentanyl is a potent synthetic opioid analgesic that is structurally related to fentanyl. It is part of the fentanyl analog family, which includes numerous compounds with similar chemical structures and pharmacological effects. Furanylfentanyl has been associated with numerous cases of overdose and fatalities due to its high potency and potential for abuse.

Chemical Structure and Properties[edit | edit source]

Furanylfentanyl is chemically known as N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide. It features a furan ring attached to the fentanyl core structure, which distinguishes it from other fentanyl analogs. The molecular formula of furanylfentanyl is C24H26N2O2.

Pharmacology[edit | edit source]

Furanylfentanyl acts as a mu-opioid receptor agonist, similar to other opioids. It binds to these receptors in the central nervous system, leading to analgesic effects, euphoria, and respiratory depression. Due to its high potency, even small doses can result in significant effects and increase the risk of overdose.

Medical Use[edit | edit source]

Furanylfentanyl has no approved medical use and is not prescribed for any medical conditions. It is primarily encountered as a recreational drug and is often found in illicit drug markets.

Legal Status[edit | edit source]

Furanylfentanyl is classified as a Schedule I controlled substance in many countries, including the United States, due to its high potential for abuse and lack of accepted medical use. This classification makes it illegal to manufacture, distribute, or possess furanylfentanyl without proper authorization.

Health Risks and Overdose[edit | edit source]

The use of furanylfentanyl carries significant health risks, including the potential for overdose and death. Symptoms of overdose may include severe respiratory depression, loss of consciousness, and death. The administration of naloxone, an opioid antagonist, can reverse the effects of an overdose if given promptly.

Detection and Analysis[edit | edit source]

Furanylfentanyl can be detected in biological samples using various analytical techniques, such as gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS). These methods are used in forensic toxicology to identify the presence of furanylfentanyl in cases of suspected overdose.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]


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Contributors: Prab R. Tumpati, MD