Gland of Zeis

Gland of Zeis

The Gland of Zeis is a type of sebaceous gland located on the margin of the eyelid. These glands are associated with the hair follicles of the eyelashes and play a crucial role in maintaining the health and function of the eyelashes.

Anatomy and Function[edit | edit source]

The Glands of Zeis are small, modified sebaceous glands that secrete an oily substance called sebum. This secretion helps to lubricate the eyelashes, preventing them from becoming dry and brittle. The sebum also plays a role in protecting the eye by forming a barrier that can trap dust and other foreign particles.

Clinical Significance[edit | edit source]

The Glands of Zeis can become blocked or infected, leading to conditions such as styes (hordeolum) or chalazions. A stye is an acute infection of the gland, often caused by Staphylococcus aureus, and presents as a painful, red swelling on the eyelid. A chalazion, on the other hand, is a chronic, non-infectious inflammation that results in a painless lump.

Related Structures[edit | edit source]

The Glands of Zeis are often mentioned alongside other eyelid glands, such as the Meibomian glands and the Gland of Moll. The Meibomian glands are larger sebaceous glands that secrete meibum, a component of the tear film, while the Glands of Moll are modified sweat glands.

Histology[edit | edit source]

Under the microscope, the Glands of Zeis appear as clusters of acini, which are small, sac-like structures that produce sebum. These acini are connected to the hair follicles of the eyelashes by short ducts.

Pathology[edit | edit source]

Blockage or dysfunction of the Glands of Zeis can lead to various eyelid disorders. Proper eyelid hygiene and treatment of underlying conditions are essential for maintaining the health of these glands.