Heinz Otto Schild

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Heinz Otto Schild (1908-1984)

Heinz Otto Schild (1906–1984) was a prominent pharmacologist known for his significant contributions to the field of pharmacology, particularly in the area of autonomic nervous system pharmacology. He is best known for developing the Schild regression, a method used to quantify the potency of antagonists in pharmacological research.

Biography[edit | edit source]

Heinz Otto Schild was born in 1906. He pursued his education in pharmacology and made significant contributions to the field throughout his career. Schild's work was instrumental in advancing the understanding of how drugs interact with receptors in the body, laying the groundwork for modern pharmacological research.

Contributions to Pharmacology[edit | edit source]

Schild's most notable contribution to pharmacology is the development of the Schild regression, a mathematical method that allows researchers to determine the potency of an antagonist by quantifying its ability to inhibit the effect of an agonist. This method has become a standard in pharmacological research, enabling scientists to more accurately study drug-receptor interactions.

In addition to the Schild regression, Heinz Otto Schild made several other contributions to the field of pharmacology, particularly in the study of the autonomic nervous system. His research helped to elucidate the mechanisms by which drugs can modulate the function of the autonomic nervous system, influencing processes such as heart rate, digestion, and respiratory rate.

Legacy[edit | edit source]

Heinz Otto Schild's work has had a lasting impact on the field of pharmacology. His development of the Schild regression has enabled countless studies on drug efficacy and potency, contributing to the development of new drugs and therapies. Schild's research on the autonomic nervous system has also provided a foundation for further study in this area, helping to improve our understanding of how drugs can be used to treat conditions related to the autonomic nervous system.

Schild's contributions to pharmacology are still recognized and celebrated today. He is remembered as a pioneer in the field, whose work has helped to shape the direction of pharmacological research for generations to come.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD