Levomethamphetamine

Levomethamphetamine.svg

Levomethamphetamine is a stereoisomer of the compound methamphetamine. It is the levorotatory (left-handed) form of methamphetamine and is used primarily as a nasal decongestant in over-the-counter inhalers.

Chemical Structure and Properties

Levomethamphetamine is a chiral molecule, meaning it has a non-superimposable mirror image. The chemical formula for levomethamphetamine is C10H15N. It is the levorotatory enantiomer of methamphetamine, which means it rotates plane-polarized light to the left. The molecular weight of levomethamphetamine is 149.23 g/mol.

Pharmacology

Levomethamphetamine acts as a sympathomimetic agent, primarily affecting the peripheral nervous system. Unlike its dextro counterpart, dextromethamphetamine, which has significant central nervous system (CNS) stimulant effects, levomethamphetamine has minimal CNS activity. This makes it suitable for use in nasal decongestants without the risk of significant stimulant side effects.

Medical Uses

Levomethamphetamine is commonly found in over-the-counter nasal decongestant inhalers. It works by constricting the blood vessels in the nasal passages, leading to reduced swelling and congestion. It is often used to relieve symptoms of nasal congestion associated with common cold, sinusitis, and allergic rhinitis.

Side Effects

Common side effects of levomethamphetamine include dry mouth, nervousness, and insomnia. Because it is a sympathomimetic agent, it can also cause increased heart rate and blood pressure. Long-term use or abuse of levomethamphetamine can lead to more serious side effects, including cardiovascular problems.

Legal Status

Levomethamphetamine is regulated differently depending on the country. In the United States, it is available over-the-counter in nasal decongestant inhalers. However, due to its structural similarity to methamphetamine, it is subject to certain restrictions to prevent misuse.

See Also

• Methamphetamine
• Dextromethamphetamine
• Nasal decongestant
• Sympathomimetic drug
• Chirality (chemistry)

External Links

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