N-Phenylacetyl-L-prolylglycine ethyl ester
N-Phenylacetyl-L-prolylglycine ethyl ester (Noopept) is a nootropic agent that was patented in Russia and the United States. It is a prodrug of cycloprolylglycine, and shares similar mechanisms of action, but is much more potent by weight.
Chemistry[edit | edit source]
N-Phenylacetyl-L-prolylglycine ethyl ester is a synthetic molecule consisting of a phenylacetyl group bound to the amino terminal of a prolylglycine peptide. This structure is thought to be responsible for its nootropic effects.
Pharmacology[edit | edit source]
Noopept has been found to have various effects in the brain. It is thought to increase the expression of two neurotrophins, brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), which play important roles in cognition and memory processes.
Clinical Use[edit | edit source]
Noopept is used in Russia and certain Eastern European countries as a nootropic agent. It is prescribed for its potential to improve memory and cognitive function. However, clinical studies on its efficacy are limited and further research is needed.
Side Effects[edit | edit source]
Common side effects of Noopept include headache, fatigue, nausea, and irritability. In rare cases, it can cause allergic reactions or skin rashes.
See Also[edit | edit source]
References[edit | edit source]
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