Orphenadrine hydrochloride

Orphenadrine Hydrochloride is a muscle relaxant and anticholinergic agent, commonly used to relieve pain and discomfort caused by strains, sprains, and other muscle injuries. It is often used in combination with rest, physical therapy, and other treatments.

Pharmacology

Orphenadrine Hydrochloride works by blocking certain nerve impulses sent to the brain, which helps to reduce muscle tension and pain. It is a derivative of diphenhydramine, an antihistamine, and shares many of its properties, including anticholinergic effects.

Medical Uses

Orphenadrine Hydrochloride is primarily used to treat muscle spasms and to relieve pain and stiffness in muscles. It is also used off-label for the treatment of Parkinson's disease due to its anticholinergic effects.

Side Effects

Common side effects of Orphenadrine Hydrochloride include dry mouth, dizziness, drowsiness, upset stomach, constipation, and blurred vision. In rare cases, it can cause severe side effects such as mental/mood changes, difficulty urinating, and fast/irregular heartbeat.

Interactions

Orphenadrine Hydrochloride can interact with other medications, including other anticholinergic drugs, antihistamines, and certain antidepressants. It is important to inform healthcare providers of all medications being taken to avoid potential interactions.

See Also

• Muscle relaxant
• Anticholinergic
• Parkinson's disease