Procyclidine hydrochloride

Procyclidine Hydrochloride is a type of anticholinergic medication primarily used in the treatment of Parkinson's disease and certain extrapyramidal symptoms associated with antipsychotic medications. It is also known by the brand name Kemadrin.

Pharmacology[edit | edit source]

Procyclidine Hydrochloride works by blocking the action of a neurotransmitter called acetylcholine in the central and peripheral nervous system. This helps to reduce muscle stiffness, tremors, and spasms associated with Parkinson's disease and extrapyramidal symptoms.

Uses[edit | edit source]

Procyclidine Hydrochloride is used to treat the symptoms of Parkinson's disease and extrapyramidal symptoms caused by antipsychotic medications. These symptoms can include involuntary movements, restlessness, and muscle stiffness. It is also sometimes used to treat similar symptoms in other conditions, such as dystonia and akathisia.

Side Effects[edit | edit source]

Like all medications, Procyclidine Hydrochloride can cause side effects. These can include dry mouth, blurred vision, constipation, difficulty urinating, and confusion. In rare cases, it can cause more serious side effects such as hallucinations, severe stomach pain, and difficulty breathing.

Interactions[edit | edit source]

Procyclidine Hydrochloride can interact with other medications, including other anticholinergic drugs, certain antihistamines, and some medications for depression and mental illnesses. It is important to inform your doctor of all medications you are currently taking before starting treatment with Procyclidine Hydrochloride.

Dosage[edit | edit source]

The dosage of Procyclidine Hydrochloride will depend on the individual patient's condition and response to treatment. It is usually taken three to four times a day, either with or without food.