SLC17A3

SLC17A3 is a gene that in humans encodes a protein known as sodium-dependent phosphate transport protein 4. This protein is a member of the solute carrier family 17. The SLC17A3 gene is located on the long (q) arm of chromosome 6 at position 16.3.

Function

The SLC17A3 gene provides instructions for making a protein that is found in the kidneys. This protein, known as sodium-dependent phosphate transport protein 4, plays a crucial role in the reabsorption of phosphate in the kidneys. It helps to control the amount of phosphate that is excreted in the urine.

Clinical significance

Mutations in the SLC17A3 gene have been associated with hyperuricemia and gout. Hyperuricemia is a condition characterized by high levels of uric acid in the blood, which can lead to the formation of uric acid crystals in the joints, causing gout.

See also

• Solute carrier family
• Hyperuricemia
• Gout
• Chromosome 6

External links

• NCBI Gene
• Genetics Home Reference

SLC17A3 Resources
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