Vestura

Vestura is a birth control pill that is categorized under the group of medications known as combined oral contraceptives. This medication is primarily used for the prevention of pregnancy. It contains two active ingredients: ethinyl estradiol, a synthetic form of the female hormone estrogen, and drospirenone, a synthetic form of the hormone progestin. These components work together to prevent ovulation (the release of an egg from an ovary) and cause changes in the cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Composition and Dosage

Vestura's active ingredients are ethinyl estradiol and drospirenone. The typical dosage form is a 28-day pill pack, which includes 21 active pills containing hormones and 7 inactive pills (placebo) without hormones. The placebo pills are included to maintain the habit of taking a pill daily and to allow a menstrual period to occur during this week.

Mechanism of Action

Vestura works by several mechanisms to prevent pregnancy. Firstly, it inhibits ovulation, ensuring that no egg is available for fertilization. Secondly, it thickens the cervical mucus, which acts as a barrier to sperm, preventing sperm from entering the uterus. Lastly, it alters the lining of the uterus, making it less receptive to an embryo, thereby preventing implantation should fertilization occur.

Indications

Vestura is indicated for the prevention of pregnancy in women who choose to use oral contraceptives as a method of contraception. Like other combined oral contraceptives, it may also be prescribed for the management of acne in women who seek contraception and have no contraindications to hormonal therapy, and for the treatment of symptoms of premenstrual dysphoric disorder (PMDD) in women who choose to use oral contraceptives.

Contraindications and Cautions

Vestura, like other combined oral contraceptives, is contraindicated in individuals with a history of thrombotic disorders, breast cancer, or other estrogen- or progestin-sensitive cancers, and in those with uncontrolled hypertension. It is also contraindicated in women over 35 years of age who smoke, due to an increased risk of cardiovascular events. Caution is advised when prescribing Vestura to women with a history of depression, as hormonal contraceptives can sometimes exacerbate depressive symptoms.

Side Effects

Common side effects of Vestura include nausea, vomiting, headache, bloating, breast tenderness, and changes in weight or appetite. More serious side effects, though rare, include an increased risk of blood clots, stroke, and heart attack, especially in smokers and women over 35.

Interactions

Vestura may interact with other medications, leading to decreased effectiveness of either the contraceptive or the other medication. It is important to inform healthcare providers of all medications being taken, including over-the-counter drugs and herbal supplements. Some medications known to interact with Vestura include certain antibiotics, anticonvulsants, and HIV medications.

Conclusion

Vestura is a combined oral contraceptive that offers an effective means of preventing pregnancy, along with additional benefits for managing acne and PMDD symptoms in women who are suitable candidates for hormonal contraception. However, it is important to consider the potential risks and side effects, and to discuss these with a healthcare provider to ensure that Vestura is the right contraceptive choice.