File:CLC-5 Mutations.jpg

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Description	Three-dimensional homology model of human CLC-5 based on the structure of ClC-ec1 (7) showing the locations of each mutated residue. Mutations are color coded according to their class; class 1 (red), class 2 (blue), and class 3 (green) and are shown with side chains in space fill. Views of the CLC-5 dimer observed from the side (A) demonstrate the location of all mutations near the subunit interface. Views from the extracellular face (B) and of the subunit interface (C) demonstrate a clear distinction in the distributions of each class of mutations. Only a single subunit is shown in B and C for clarity.
Author or copyright owner	American Journal of Physiology
Source (WP:NFCC#4)	http://ajprenal.physiology.org/content/296/2/F390/F6.expansion
Date of publication	n/a
Use in article (WP:NFCC#7)	Dent's disease
Purpose of use in article (WP:NFCC#8)	The mutation of the CLC-5 gene responsible for Dent's Disease
Not replaceable with free media because (WP:NFCC#1)	n.a.
Minimal use (WP:NFCC#3)	The article is not reproducing the entire power point teaching slide of this topic, rather the model of the genetic mutation is being used in the article for educational purposes.
Respect for commercial opportunities (WP:NFCC#2)	n.a.
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	Date/Time	Thumbnail	Dimensions	User	Comment
current	13:51, 7 January 2017		302 × 330 (21 KB)	DatBot	Reduce size of non-free image (BOT - disable)

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