File:Regulation of P13K-Akt Pathway in Feedback Loops.png

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Regulation_of_P13K-Akt_Pathway_in_Feedback_Loops.png(614 × 559 pixels, file size: 91 KB, MIME type: image/png)

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Examples of the feedback loops regulating the P13K-Akt pathway. Akt activation suppresses PTEN via NF-κB, allowing further activation (positive feedback). Akt activation also suppresses P13K via mTOR and IRS-1, preventing further activation (negative feedback).

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current23:04, 25 March 2015Thumbnail for version as of 23:04, 25 March 2015614 × 559 (91 KB)TbatanExamples of the feedback loops regulating the P13K-Akt pathway. Akt activation suppresses PTEN via NF-κB, allowing further activation (positive feedback). Akt activation also suppresses P13K via mTOR and IRS-1, preventing further activation (negative...

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