File:Septins and TTFields.jpg

No higher resolution available.

Septins_and_TTFields.jpg ‎(776 × 504 pixels, file size: 95 KB, MIME type: image/jpeg)

This file is from a shared repository and may be used by other projects. The description on its file description page there is shown below.

Wikipedia does not have a File page with this exact name.

Other reasons this message may be displayed:

If an image was recently created here, it may not be visible yet because of a delay in updating the database; wait a few minutes or try the purge function.
Titles on Wikipedia are case sensitive except for the first character; please check alternative capitalizations and consider adding a redirect here to the correct title.
If the page has been deleted, check the deletion log, and see Why was the page I created deleted?

File history

Click on a date/time to view the file as it appeared at that time.

	Date/Time	Thumbnail	Dimensions	User	Comment
current	20:17, 4 December 2023		776 × 504 (95 KB)	Novafields	Uploaded a work by Nidhi Gera from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444126/ with UploadWizard

The following file is a duplicate of this file (more details):

The following page uses this file:

This file contains additional information, probably added from the digital camera or scanner used to create or digitize it.

If the file has been modified from its original state, some details may not fully reflect the modified file.

Image title	Model for TTFields action leading to mitotic disruption.During mitosis, the Septin 2, 6, 7 complex is recruited to the Anaphase spindle midline and the cytokinetic cleavage furrow by Anillin where it self-assembles into a fibrous lattice due to lateral interactions between parallel Septin filaments. By inducing rotational movement within the parallel fibers at a slightly less more than a right angle to their lateral axis, TTFields are able to inhibit the propagation of lattice formation by disrupting the ability of individual fibers to bind each other. In the absence of proper Septin function, contractile elements of the cytokinetic furrow are not restrained within the equatorial midline of the cell resulting in ectopic furrow malfunction that leads to violent membrane contractions at the onset of anaphase followed by aberrant mitotic exit.
Copyright holder	Creative Commons Attribution License
Date(s)	26 May 2015
Publisher	Public Library of Science
Short title	Fig 5
Source	info:doi/10.1371/journal.pone.0125269
Identifier	info:doi/info:doi/10.1371/journal.pone.0125269.g005