Alcuronium chloride

Alcuronium chloride is a type of neuromuscular-blocking drug or muscle relaxant that was introduced to anesthesia practice in the 1960s. It is a semi-synthetic substance derived from toxiferine, a curare alkaloid.

Etymology

The name "Alcuronium" is derived from the chemical structure of the compound. The "Alc" part of the name comes from the alcohols used in its synthesis, while the "uronium" part refers to its quaternary ammonium structure.

Pharmacology

Alcuronium chloride acts as a non-depolarizing neuromuscular blocking agent. It works by blocking the action of acetylcholine, a neurotransmitter that transmits signals in the nervous system. By blocking acetylcholine, alcuronium chloride prevents the transmission of signals from the nerves to the muscles, resulting in muscle relaxation.

Medical Uses

Alcuronium chloride is used in medicine to relax muscles during surgery. It is also used in intensive care units to facilitate intubation or mechanical ventilation.

Side Effects

Possible side effects of alcuronium chloride include hypotension, tachycardia, and bronchospasm. It can also cause an allergic reaction in some patients.

Related Terms

• Neuromuscular-blocking drug
• Muscle relaxant
• Toxiferine
• Acetylcholine
• Hypotension
• Tachycardia
• Bronchospasm

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