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File:Glutamate-gated chloride channel receptor with bound ivermectin 3RHW.png
From WikiMD's Food, Medicine & Wellness Encyclopedia
Size of this preview: 291 × 599 pixels. Other resolution: 1,200 × 2,470 pixels.
Original file (1,200 × 2,470 pixels, file size: 2.32 MB, MIME type: image/png)
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 17:49, 29 November 2020 | 1,200 × 2,470 (2.32 MB) | Fvasconcellos | {{Information |Description=Top-down and side views of the ''C. elegans'' glutamate-gated chloride channel receptor (GluClR), a pentameric ligand-gated ion channel, bound to {{w|ivermectin}}. Ivermectin (royal blue) interacts with a binding pocket formed by the transmembrane domains of adjacent GluClR subunits (pale blue), "locking" the receptor in an activated (open) conformation that allows unrestricted passage of chloride (Cl<sup>−</sup>) ions into the cell. C... |
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