File:Grade 4 partial androgen insensitivity syndrome.jpg

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Grade_4_partial_androgen_insensitivity_syndrome.jpg(416 × 239 pixels, file size: 25 KB, MIME type: image/jpeg)

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Summary

Description

Grade 4 PAIS with bifid scrotum, microphallus-like clitoris, and urethral orifice with terminal sinus urogenitalis.

Source

Aguilar-Ponce J, Chilaca Rosas F, Molina Calzada C, Granados García M, Jiménez Ríos MA, De la Garza Salazar J. Testicular cancer in androgen insensitivity syndrome in a Mexican population. Clin Transl Oncol. 2008;10:840-843.

Article

Partial androgen insensitivity syndrome

Portion used

Single image from an article in a medical journal.

Low resolution?

Resolution of this image will not affect journal subscriptions (i.e. revenue).

Purpose of use

This image helps grade 4 PAIS patients make medical decisions (e.g. type and extent of genitoplasty) by clearly illustrating the surgically unaltered genitalia of an individual with grade 4 PAIS. This kind of information is very difficult to get.

Replaceable?

PAIS is a very rare disorder, affecting approximately 1 in 100,000 births. This particular variant (grade 4) rare even among individuals with PAIS. Many will have genitplastic surgery shortly after puberty, making this photograph exceedingly rare, and very unlikely that it can be replaced. It is also worthy to note that this subject is sensitive, and calls for medical quality photography.

Other information

Sources that describe PAIS and its rarity include: (1:) Quigley CA, De Bellis A, Marschke KB, El-Awady MK, Wilson EM, French FS. Androgen receptor defects: historical, clinical, and molecular perspectives. Endocr Rev. 1995;16:271–321. (2:)Mazen I, El-Ruby M, Kamal R, El-Nekhely I, El-Ghandour M, Tantawy S, El-Gammal M. Screening of Genital Anomalies in Newborns and Infants in Two Egyptian Governorates. Horm Res Paediatr. 2010;73:438-442.

Fair useFair use of copyrighted material in the context of Partial androgen insensitivity syndrome//en.wikipedia.org/wiki/File:Grade_4_partial_androgen_insensitivity_syndrome.jpgtrue

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Date/TimeThumbnailDimensionsUserComment
current02:01, 4 June 2017Thumbnail for version as of 02:01, 4 June 2017416 × 239 (25 KB)DatBotReduce size of non-free image (BOT - disable)

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