File:Mild androgen insensitivity syndrome.jpg
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Summary
Description
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Mild androgen insensitivity syndrome (MAIS) presenting with a mild impairment of virilization in a 23-year-old man.
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Source
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Pinsky L, Kaufman M, Killinger DW, Opitz JM, Reynolds JF. Impaired spermatogenesis is not an obligate expression of receptor-defective androgen resistance. Am J Med Genet. 1989;32:100-104.
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Article
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Mild androgen insensitivity syndrome
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Portion used
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Single image from an article in a medical journal.
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Low resolution?
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Resolution of this image will not affect journal subscriptions (i.e. revenue).
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Purpose of use
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This image illustrates the hallmarks of mild androgen insensitivity syndrome: virilization (body hair, etc.) is impaired in this 23-year old man, but genital masculinization has taken place normally. This image also serves to illustrate the subtle presentation of MAIS, making it clear that seemingly "normal" men can have MAIS.
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Replaceable?
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MAIS is so rare that its true incidence is unknown, although it is thought to occur less frequently that PAIS, which is estimated to occur in approximately once every 100,000 births. This particular image is the only image I have ever seen of the body of an individual with confirmed MAIS, making this photograph exceedingly rare, and very unlikely that it can be replaced. It is also worthy to note that this subject is sensitive, and calls for medical quality photography.
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Other information
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Sources that describe MAIS and its rarity include: (1:) Zuccarello D, Ferlin A, Vinanzi C, Prana E, Garolla A, Callewaert L, Claessens F, Brinkmann AO, Foresta C. Detailed functional studies on androgen receptor mild mutations demonstrate their association with male infertility. Clin Endocrionol. 2008;68:580-588. (2:) Ferlin A, Vinanzi C, Garolla A, Selice R, Zuccarello D, Cazzadore C, Foresta C. Male infertility and androgen receptor gene mutations: clinical features and identification of seven novel mutations. Clin Endocrinol. 2006;65:606–610. (3:) Hughes I, Deeb A. Androgen resistance. Best Pract Res Clin Endocrinol Metab. 2006;20:577-598.
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Fair useFair use of copyrighted material in the context of Mild androgen insensitivity syndrome//en.wikipedia.org/wiki/File:Mild_androgen_insensitivity_syndrome.jpgtrue
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Licensing
 | This image is a scan of a newspaper page or article, and the copyright for it is most likely held by either the publisher of the newspaper or the individual contributors who worked on the articles or images depicted. It is believed that the use of low-resolution images of newspaper pages
- to illustrate either the publication of the article or issue in question,
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qualifies as fair use under the copyright law of the United States. Any other uses of this image, on Wikipedia or elsewhere, may be copyright infringement. See Wikipedia:Non-free content for more information.
Note: If the image depicts a person or persons on the cover, it is not acceptable to use the image in the article of the person or persons depicted on the cover, unless used to directly illustrate a point about the publication of the image. Use of the image merely to depict a person or persons in the image will be removed.
Fair use
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment |
current | 23:14, 3 January 2018 |  | 233 × 427 (14 KB) | DatBot | Reduce size of non-free image (BOT - disable) |
File usage
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