Pyridoxine

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Pyridoxine[edit | edit source]

Introduction[edit | edit source]

Pyridoxine, also known as vitamin B6, is one of the vitamins included in the B complex family. It plays a vital role in a wide range of physiological functions, including amino acid metabolism, neurotransmitter synthesis, and hemoglobin production.

Chemical Properties[edit | edit source]

Pyridoxine is a water-soluble vitamin. Its chemical formula is C8H11NO3, and it exists in several forms, including pyridoxal, pyridoxamine, and pyridoxal phosphate, which is the active coenzyme form.

Dietary Sources[edit | edit source]

Good dietary sources of pyridoxine include:

  • Poultry, fish, and liver.
  • Starchy vegetables like potatoes.
  • Non-citrus fruits.
  • Fortified cereals and grains.
Various foods high in Pyridoxine.

Biological Functions[edit | edit source]

Pyridoxine is essential for:

  • Protein and carbohydrate metabolism.
  • The creation of red blood cells and neurotransmitters.
  • Immune function.
  • Brain development during pregnancy and infancy.

Health Benefits[edit | edit source]

Adequate pyridoxine intake is associated with potential health benefits, including:

  • Reducing the risk of heart disease.
  • Supporting brain health and mood regulation.
  • Alleviating symptoms of premenstrual syndrome (PMS).

Pyridoxine Deficiency[edit | edit source]

Deficiency of pyridoxine, though rare, can lead to:

  • Anemia.
  • Skin disorders.
  • Neurological symptoms like depression and confusion.
  • Weakened immune function.

Toxicity and Overdose[edit | edit source]

While pyridoxine is generally safe, excessive intake can lead to neuropathy and other health issues. Supplementation should be monitored, especially for high doses.

Pyridoxine in Medicine[edit | edit source]

In medical contexts, pyridoxine is used:

  • To treat or prevent pyridoxine deficiency.
  • As a treatment for certain metabolic disorders.
  • To prevent or treat side effects of certain medications like isoniazid.

See Also[edit | edit source]

References[edit | edit source]


External Links[edit | edit source]

Pyridoxine Resources
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Contributors: Prab R. Tumpati, MD