Cefapirin

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Cefapirin is a first-generation cephalosporin antibiotic. It was first introduced in 1964 and is no longer in common use in the United States. It is an antibiotic that is categorized under the cephalosporin class of antibiotics.

Indications[edit | edit source]

Cefapirin is used to treat a variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu).

Mechanism of Action[edit | edit source]

Like other cephalosporins, cefapirin works by inhibiting the synthesis of the bacterial cell wall, leading to cell death.

Side Effects[edit | edit source]

Side effects of cefapirin can include nausea, vomiting, diarrhea, and allergic reactions. Serious side effects can include Clostridium difficile-associated diarrhea (CDAD) and allergic reactions.

Contraindications[edit | edit source]

Cefapirin is contraindicated in patients with a known allergy to cephalosporin antibiotics.

Drug Interactions[edit | edit source]

Cefapirin may interact with other medications, including probenecid, which can slow down the removal of cefapirin from the body and result in increased levels of the drug.

See Also[edit | edit source]

References[edit | edit source]


External Links[edit | edit source]

Cefapirin Resources
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Contributors: Prab R. Tumpati, MD