Penicillin g potassium

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Penicillin G potassium is a type of antibiotic that is used to treat a variety of bacterial infections. It is a member of the penicillin family of antibiotics, which are derived from the fungus Penicillium. Penicillin G potassium works by inhibiting the synthesis of bacterial cell walls, leading to the death of the bacteria.

History[edit | edit source]

Penicillin G potassium was first discovered in 1928 by Alexander Fleming. He noticed that a culture of Staphylococcus bacteria had been contaminated by a Penicillium fungus, and that the bacteria around the fungus had died. This led to the discovery of penicillin, the first antibiotic.

Medical uses[edit | edit source]

Penicillin G potassium is used to treat a variety of bacterial infections, including pneumonia, meningitis, endocarditis, and syphilis. It is also used to prevent bacterial endocarditis in people who are undergoing dental or surgical procedures.

Side effects[edit | edit source]

Like all antibiotics, penicillin G potassium can cause side effects. These can include allergic reactions, nausea, vomiting, and diarrhea. In rare cases, it can cause serious side effects such as anaphylaxis, a severe allergic reaction.

Resistance[edit | edit source]

Over time, some bacteria have developed antibiotic resistance to penicillin G potassium. This means that the antibiotic is no longer effective against these bacteria. Resistance can occur when bacteria mutate, or when they acquire resistance genes from other bacteria.

See also[edit | edit source]



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Contributors: Prab R. Tumpati, MD