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  • 3-hydroxyisobutyryl-CoA hydrolase
    [[File:3bpt.jpg|3bpt|thumb]] '''3-Hydroxyisobutyryl-CoA hydrolase''' is an [[enzyme]] that plays a crucial role in the [[metabolism]] of [[am The primary function of 3-hydroxyisobutyryl-CoA hydrolase is to facilitate the conversion of 3-hydroxyisobutyryl-CoA, a byproduct of
    3 KB (345 words) - 19:55, 23 April 2024
  • Hydrolase inhibitors
    ...ipids]], [[proteins]], and [[nucleic acids]]. By inhibiting these enzymes, hydrolase inhibitors can affect various physiological and pathological processes, mak ==Types of Hydrolase Inhibitors==
    3 KB (464 words) - 03:27, 2 April 2024
  • Hydroxyacylglutathione hydrolase
    ...xification. Hydroxyacylglutathione hydrolase catalyzes the conversion of [[S-D-lactoylglutathione]] to [[glutathione]] and [[D-lactic acid]], a key step ...and [[lipids]], leading to cellular dysfunction and disease. By converting S-D-lactoylglutathione to glutathione and D-lactic acid, HAGH helps to preven
    2 KB (304 words) - 03:32, 28 March 2024
  • HIBCH deficiency
    ...e to 3-hydroxyisobutyryl-CoA hydrolase deficiency; 3-Hydroxyisobutyryl-CoA hydrolase deficiency; Beta-hydroxyisobutyryl-CoA deacylase deficiency; Methacrylic ac ...uild up of toxic valine metabolites within the mitochondria''' in the body's cells.
    5 KB (667 words) - 18:05, 27 March 2021
  • Bleomycin hydrolase
    ...ticular cancer]], and certain types of [[head and neck cancer]]. Bleomycin hydrolase is a [[cysteine peptidase]] that belongs to the family of [[hydrolases]], e ...l]] homeostasis and has been implicated in the pathogenesis of [[Alzheimer's disease]] due to its ability to degrade amyloid peptides.
    3 KB (380 words) - 19:56, 17 March 2024
  • Cellulose-polysulfatase
    ...stematic name of this enzyme class is cellulose-polysulfate sulfuric-ester hydrolase. ...ions and reducing the polysaccharide to its constituent [[monosaccharide]]s.
    2 KB (196 words) - 08:10, 11 March 2024
  • ABHD3
    ...ydrolase domain-containing protein 3) is an enzyme that belongs to the α/β hydrolase superfamily. It plays a crucial role in various biological processes, inclu ...encoded by ABHD3 consists of 356 amino acids and contains a conserved α/β hydrolase domain.
    3 KB (342 words) - 18:14, 21 January 2024
  • 3-Hydroxyisobutyryl-CoA deacylase deficiency
    ...2014) Clinical and biochemical characterization of 3-hydroxyisobutyryl-CoA hydrolase (HIBCH) deficiency that causes Leigh-like disease and ketoacidosis. Mol Gen
    3 KB (361 words) - 04:21, 28 November 2020
  • Sphingolipid metabolism
    ...egins with the removal of the head group of the sphingolipid by a specific hydrolase. The resulting ceramide is then hydrolyzed by [[ceramidase]] to yield sphin ...es, including [[Gaucher's disease]], [[Niemann-Pick disease]], and [[Fabry's disease]]. These disorders, known as [[sphingolipidoses]], are characterize
    3 KB (335 words) - 20:54, 29 February 2024
  • Choloylglycine hydrolase
    '''Choloylglycine hydrolase''' (CGH) is an [[enzyme]] that plays a crucial role in the metabolism of [[ ...ontributes to their recycling, a process critical for maintaining the body's bile acid pool and ensuring efficient fat digestion.
    3 KB (477 words) - 02:02, 11 April 2024
  • Hypermethioninemia due to S-adenosylhomocysteine hydrolase deficiency
    ...e deficiency; Hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase Hypermethioninemia due to S-adenosylhomocysteine hydrolase deficiency (SAHH deficiency) is a muscle disease associated with high blood
    3 KB (393 words) - 15:03, 28 March 2021
  • Pyroglutamyl-peptidase I
    ...systematic name of this enzyme class is ''N-terminal-pyroglutamyl-peptide hydrolase''. ...tidase I is involved in the metabolism of [[neuropeptide]]s and [[hormone]]s, many of which have an N-terminal pyroglutamyl residue. This residue is imp
    2 KB (202 words) - 21:03, 10 March 2024
  • Diisopropyl-fluorophosphatase
    ...sed of a single polypeptide chain, which folds into a compact [[alpha/beta hydrolase]] fold. The active site of the enzyme is located in a deep pocket within th ...dering them harmless. This makes DFPase an important component of the body's defense mechanism against organophosphate poisoning.
    2 KB (207 words) - 06:27, 11 March 2024
  • Imidazolonepropionase
    ...wn as '''imidazolone 5-propionate hydrolase''' or '''imidazolonepropionate hydrolase'''.
    2 KB (187 words) - 10:52, 11 March 2024
  • Endo-beta-(1-6)-galactanase
    ...rolase|hydrolases]], specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is (1->6)-beta * [[Hydrolase]]
    2 KB (215 words) - 08:12, 11 March 2024
  • Glutamate carboxypeptidase II
    ...' (NAALADase), is an enzyme that in humans is encoded by the FOLH1 (Folate hydrolase 1) gene. It is a type II transmembrane glycoprotein that is expressed in va In the kidney, GCPII functions as a folate hydrolase, involved in the uptake of dietary folates. In the prostate, it has been id
    2 KB (238 words) - 17:03, 1 February 2024
  • 3-Deazaneplanocin A
    ...tent inhibitor of the [[enzyme]] [[S-adenosylhomocysteine hydrolase]] (SAH hydrolase), which plays a crucial role in the regulation of [[methylation]] processes ...in the concentration of [[S-adenosylhomocysteine]] (SAH), a byproduct of [[S-adenosylmethionine]] (SAM)-dependent methylation reactions. Elevated levels
    3 KB (412 words) - 10:48, 19 April 2024
  • Gamma-glutamyl hydrolase
    ...GGH) is an enzyme that plays a crucial role in the metabolism of [[folate]]s, a group of water-soluble B-vitamins that are essential for the synthesis a Gamma-glutamyl hydrolase is primarily involved in the [[Folate metabolism|metabolism of folates]], c
    3 KB (425 words) - 10:31, 19 March 2024
  • URB597
    ...University of Urbino]], Italy. The compound was named after the university's initials and the number of the compound in the series of FAAH inhibitors th URB597 works by inhibiting the [[fatty acid amide hydrolase]] (FAAH), an enzyme that breaks down anandamide. By inhibiting FAAH, URB597
    2 KB (261 words) - 19:45, 29 February 2024
  • BIA 10-2474
    ...a range of different medical conditions from anxiety disorder to Parkinson's disease, also for the treatment of chronic pain of multiple sclerosis, canc
    771 bytes (111 words) - 00:26, 21 February 2024

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