Panipenem/betamipron
(Redirected from Carbenin)
Panipenem/betamipron is a combination medication used in the treatment of various bacterial infections. It contains two active ingredients: panipenem, a carbapenem antibiotic, and betamipron, a renal dehydropeptidase inhibitor.
Etymology[edit | edit source]
The name "panipenem" is derived from the Greek words "pani-", meaning "all", and "penem", a suffix used in the names of many beta-lactam antibiotics. The name "betamipron" is a portmanteau of "beta", referring to its action on beta-lactamase enzymes, and "mipron", a suffix used in the names of many synthetic drugs.
Pharmacology[edit | edit source]
Panipenem is a broad-spectrum carbapenem antibiotic that works by inhibiting the synthesis of bacterial cell walls, leading to cell death. Betamipron is a renal dehydropeptidase inhibitor that protects panipenem from being metabolized and deactivated in the kidneys, thereby increasing its effectiveness.
Clinical Use[edit | edit source]
Panipenem/betamipron is used to treat a wide range of bacterial infections, including those caused by Gram-positive bacteria, Gram-negative bacteria, and anaerobic bacteria. It is particularly effective against infections caused by bacteria that are resistant to other antibiotics.
Side Effects[edit | edit source]
Common side effects of panipenem/betamipron include nausea, diarrhea, and skin rash. In rare cases, it can cause serious side effects such as seizures, severe allergic reactions, and Clostridium difficile-associated diarrhea.
Related Terms[edit | edit source]
- Carbapenem: A class of antibiotics to which panipenem belongs.
- Beta-lactam: A class of antibiotics that includes carbapenems, penicillins, and cephalosporins.
- Renal dehydropeptidase: An enzyme found in the kidneys that metabolizes certain drugs, including panipenem.
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