Cytochrophin-4

From WikiMD's Food, Medicine & Wellness Encyclopedia

Cytochrophin-4 is a protein that in humans is encoded by the CTHRC1 gene. It is a secreted protein that is overexpressed in many cancer types and promotes cell migration and adhesion.

Function[edit | edit source]

Cytochrophin-4 is a protein that is encoded by the CTHRC1 gene in humans. It is a secreted protein that is overexpressed in many types of cancer and promotes cell migration and adhesion. The protein is known to inhibit collagen expression and osteoblast differentiation. It is also involved in the Wnt signaling pathway, which plays a crucial role in tissue regeneration and cancer progression.

Clinical significance[edit | edit source]

Overexpression of Cytochrophin-4 has been observed in various types of cancer, including breast cancer, colorectal cancer, and hepatocellular carcinoma. It is believed to promote cancer progression by enhancing cell migration and adhesion. Therefore, it is considered a potential target for cancer therapy.

See also[edit | edit source]

Cytochrophin-4 Resources
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Contributors: Prab R. Tumpati, MD