Ethinylestradiol sulfonate/norethisterone acetate
Ethinylestradiol sulfonate/norethisterone acetate is a combined oral contraceptive pill that is used for the prevention of pregnancy. It contains two active ingredients, ethinylestradiol sulfonate and norethisterone acetate, which are synthetic versions of the naturally occurring female sex hormones, estrogen and progesterone.
Etymology[edit | edit source]
The term "ethinylestradiol" is derived from the words "ethynyl", referring to the ethynyl group present in the chemical structure, and "estradiol", which is a type of estrogen. "Sulfonate" refers to the sulfonate group that is added to the ethinylestradiol to increase its water solubility. "Norethisterone" is derived from "nor-", indicating a demethylated ethisterone, and "ethisterone", a progestin that was used in the first orally effective progestogen-only contraceptive.
Pharmacology[edit | edit source]
Ethinylestradiol sulfonate is a synthetic estrogen that works by preventing the release of an egg from the ovaries. Norethisterone acetate is a synthetic progestogen that works by thickening the mucus in the cervix, making it difficult for sperm to reach an egg, and thinning the lining of the womb, making it less likely for a fertilized egg to implant and grow.
Usage[edit | edit source]
This medication is taken orally, usually once a day. It is important to take it at the same time each day to ensure consistent levels of the hormones in the body. If a dose is missed, it should be taken as soon as remembered, and the next dose should be taken at the usual time.
Side Effects[edit | edit source]
Common side effects of ethinylestradiol sulfonate/norethisterone acetate include nausea, vomiting, headache, bloating, breast tenderness, and weight change. Serious side effects are rare, but may include blood clots, stroke, and heart attack.
Related Terms[edit | edit source]
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