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N-sulfoglucosamine-3-sulfatase
...dase''') is an [[enzyme]] that is involved in the degradation of [[heparan sulfate]] in [[lysosome]]s. This enzyme is encoded by the SGSH gene in humans. Defi ...s, with N-sulfoglucosamine-3-sulfatase acting at a specific step to remove sulfate groups.

2 KB (228 words) - 06:39, 11 March 2024
Heparan sulfate
...y critical roles in cell signaling, coagulation, and inflammation. Heparan sulfate is unique among GAGs due to its highly variable sulfation patterns, which c Heparan sulfate is composed of a repeating disaccharide unit of [[glucuronic acid]] (GlcA)

3 KB (453 words) - 07:03, 22 March 2024
NAGLU
...glucosaminidase]]. This enzyme is involved in the degradation of [[heparan sulfate]], a type of [[glycosaminoglycan]] found in the [[extracellular matrix]] of ...glycans]] (GAGs). Specifically, it helps break down a GAG called [[heparan sulfate]].

2 KB (254 words) - 05:37, 10 March 2024
N-acetylgalactosaminoglycan deacetylase
...cans, such as [[chondroitin sulfate]], [[dermatan sulfate]], and [[heparan sulfate]], are involved in various biological processes, including cell signaling,

2 KB (292 words) - 04:27, 11 April 2024
Syndecan 1
...tion of the protein is modified with [[heparan sulfate]] and [[chondroitin sulfate]] chains, which are involved in binding to other molecules in the extracell

2 KB (219 words) - 12:39, 10 March 2024
Syndecan-1
...minal segment, a longer segment containing heparan sulfate and chondroitin sulfate chains, and a variable region that is unique to each syndecan. The cytoplas

2 KB (253 words) - 05:48, 11 March 2024
Maroteaux–Lamy syndrome
...ncy of [[arylsulfatase B]] (ASB) leading to the accumulation of [[dermatan sulfate]]. ...ing of elevated urinary [[dermatan sulfate]] with the absence of [[heparan sulfate]] is supportive.

6 KB (856 words) - 16:56, 10 July 2020
Pick's disease
...]], [[Serum amyloid P component|amyloid P]], and [[heparan sulfate|heparan sulfate glycosaminoglycan]].<ref name = Munoz/>

20 KB (2,662 words) - 19:39, 5 March 2024
List of rare diseases-H
* '''[[Heparan sulfamidase deficiency]]''' * '''[[Heparan sulfate sulfatase deficiency]]'''

57 KB (7,147 words) - 03:26, 10 April 2022
Implantation (human embryo)
| [[heparan sulfate]]

22 KB (3,130 words) - 07:16, 23 February 2024
MeSH H
* '''[[Heparan Sulfate Proteoglycans]]''' * '''[[Heparitin Sulfate]]'''

48 KB (6,234 words) - 03:44, 10 March 2024
Antineoplastic agents uvw
* '''[[Vinblastine sulfate]]''' - The sulfate salt of vinblastine, a natural alkaloid isolated from the plant Catharanthu * '''[[Vincristine sulfate]]''' - The sulfate salt of a natural alkaloid isolated from the plant Catharanthus roseus (Vin

103 KB (14,437 words) - 01:35, 19 March 2024
Antineoplastic agents h
...mimetic m402]]''' - A low molecular weight heparin derivative and heparan sulfate proteoglycan (HSPG) mimetic with no or minimal anticoagulant activity and p

105 KB (14,813 words) - 01:33, 19 March 2024
డిక్షనరీ ఆఫ్ డ్రగ్స్:H
* '''[[Heparan sulfate glycosaminoglycan mimetic M402|హెపరాన్ సల్ఫేట్

320 KB (3,878 words) - 23:08, 6 July 2019
Dictionary-H
* [[heparan N-sulfatase]] * [[heparan sulfate]]

76 KB (5,729 words) - 02:50, 19 March 2024
Antineoplastic agents a4
...potent CTL-mediated lysis of GPC3-expressing tumor cells. GPC3, a heparan sulfate proteoglycan and an oncofetal antigen protein, is overexpressed in a variet ...PC3-expressing tumor cells, resulting in tumor cell lysis. GPC3, a heparan sulfate proteoglycan and a member of the glypican family, is overexpressed on certa

240 KB (33,186 words) - 01:36, 19 March 2024
Antineoplastic agents l
* '''[[Larotrectinib sulfate]]''' - The sulfate salt form of larotrectinib, an orally available, tropomyosin receptor kinas ...stic activity. Upon intravitreal injection, the HPV-NPs target and bind to heparan-sulfated proteoglycans (HSPG) expressed by ocular melanoma cells. Upon irra

127 KB (17,614 words) - 01:34, 19 March 2024
Antineoplastic agents r
...y of heparanase. This prevents the heparanase-mediated cleavage of heparan sulfate (HS) proteoglycans on cell surfaces and within the extracellular matrix. In

142 KB (19,609 words) - 01:34, 19 March 2024
Dictionary-of-medicine-H
* '''[[heparan]]''' * '''[[heparan n sulfatase]]'''

270 KB (39,892 words) - 20:50, 28 August 2022
Antineoplastic agents a2
...the IL-1 receptor antagonist IL-1RN. This agent also downregulates heparan sulfate and reduces the expansion of cytotoxic effector T cells, interferes with th

150 KB (20,738 words) - 01:36, 19 March 2024