XELOX
XELOX is a chemotherapy regimen for treatment of colorectal cancer. It consists of Capecitabine (Xeloda) and Oxaliplatin (Eloxatin). The regimen is considered a first-line treatment for metastatic colorectal cancer.
Treatment Regimen[edit | edit source]
The XELOX regimen is typically administered in cycles. A cycle usually lasts for three weeks. During the first day of each cycle, Oxaliplatin is given intravenously over a period of two hours. Capecitabine is taken orally twice daily for the first two weeks, followed by a week of rest.
Efficacy[edit | edit source]
Several studies have shown that XELOX is as effective as the FOLFOX regimen, another first-line treatment for metastatic colorectal cancer. The choice between XELOX and FOLFOX often depends on patient preference, side effect profile, and convenience.
Side Effects[edit | edit source]
Common side effects of the XELOX regimen include nausea, vomiting, diarrhea, fatigue, and neuropathy. Severe side effects can include neutropenia, a low white blood cell count that can increase the risk of infection.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
