XELOX

From WikiMD's Wellness Encyclopedia

XELOX is a chemotherapy regimen for treatment of colorectal cancer. It consists of Capecitabine (Xeloda) and Oxaliplatin (Eloxatin). The regimen is considered a first-line treatment for metastatic colorectal cancer.

Treatment Regimen[edit | edit source]

The XELOX regimen is typically administered in cycles. A cycle usually lasts for three weeks. During the first day of each cycle, Oxaliplatin is given intravenously over a period of two hours. Capecitabine is taken orally twice daily for the first two weeks, followed by a week of rest.

Efficacy[edit | edit source]

Several studies have shown that XELOX is as effective as the FOLFOX regimen, another first-line treatment for metastatic colorectal cancer. The choice between XELOX and FOLFOX often depends on patient preference, side effect profile, and convenience.

Side Effects[edit | edit source]

Common side effects of the XELOX regimen include nausea, vomiting, diarrhea, fatigue, and neuropathy. Severe side effects can include neutropenia, a low white blood cell count that can increase the risk of infection.

See Also[edit | edit source]





XELOX Resources

Contributors: Prab R. Tumpati, MD