CAPOX

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File:Pre and post chemotherapy colorectal cancer.png
Pre- and post-chemotherapy images of a T3 N1 M0 cStage IIIa colorectal cancer. Four courses of CAPOX therapy.

CAPOX (also called XELOX[1]) is a chemotherapy regimen consisting of capecitabine (trade name Xeloda) combined with oxaliplatin.[2][3]

Xelox regime operates in 3-week cycles, usually with 8 cycles in total; Xeloda is orally taken for twice daily for two weeks, while oxaliplatin is administrated by IV on the first day of the cycle; there is a one-week rest period before the next cycle.

Adverse effects[edit]

References[edit]

  1. "XELOX (Capecitabine Plus Oxaliplatin): Active First-Line Therapy for Patients with Metastatic Colorectal Cancer".Journal of Clinical Oncology.2004;22(11)
    2084–2091.doi:10.1200/JCO.2004.11.069.PMID:15169795.
  2. Capecitabine Combined with Oxaliplatin (CapOx) in Clinical Practice: How Significant is Peripheral Neuropathy? D. J. Storey; M. Sakala; C. M. McLean; H. A. Phillips; L. K. Dawson; L. R. Wall; M. T. Fallon; S. Clive. Posted: 09/28/2010; Annals of Oncology. 2010;21(8):1657-1661. © 2010 Oxford University Press
  3. "Capecitabine as adjuvant treatment for stage III colon cancer".N. Engl. J. Med..June 2005;352(26)
    2696–704.doi:10.1056/NEJMoa043116.PMID:15987918.