(+)-5-(1,3-Dimethylbutyl)-5-ethylbarbituric acid

From WikiMD's Food, Medicine & Wellness Encyclopedia

(+)-5-(1,3-Dimethylbutyl)-5-ethylbarbituric acid is a chemical compound belonging to the class of barbiturates. It is a synthetic derivative of barbituric acid, which is a non-proteinogenic amino acid that is the core structure of many biologically active compounds.

Structure and Properties[edit | edit source]

The structure of (+)-5-(1,3-Dimethylbutyl)-5-ethylbarbituric acid consists of a barbituric acid core, with a 1,3-dimethylbutyl group and an ethyl group attached to the 5th carbon atom. The (+) sign in the name indicates that this compound is a chiral molecule, meaning it has a non-superimposable mirror image.

The properties of (+)-5-(1,3-Dimethylbutyl)-5-ethylbarbituric acid, like other barbiturates, are largely determined by the nature and position of its substituent groups. These properties can include its solubility, melting point, and boiling point, as well as its biological activity.

Synthesis[edit | edit source]

The synthesis of (+)-5-(1,3-Dimethylbutyl)-5-ethylbarbituric acid typically involves the reaction of barbituric acid with 1,3-dimethylbutyl and ethyl groups in the presence of a suitable catalyst. The exact conditions and reagents used can vary depending on the desired yield and purity of the product.

Biological Activity[edit | edit source]

As a member of the barbiturate class of compounds, (+)-5-(1,3-Dimethylbutyl)-5-ethylbarbituric acid may exhibit sedative, hypnotic, and/or anticonvulsant activity. However, the specific biological activity of this compound has not been extensively studied and may vary depending on factors such as dosage, route of administration, and individual patient characteristics.

Safety and Toxicity[edit | edit source]

Like other barbiturates, (+)-5-(1,3-Dimethylbutyl)-5-ethylbarbituric acid has the potential for abuse and dependence. Overdose can result in severe respiratory depression, coma, and death. Therefore, use of this compound should be closely monitored by a healthcare professional.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD