3-Chloromethcathinone

From WikiMD's Food, Medicine & Wellness Encyclopedia

Synthesis of 3-CMC
Metabolism 3-CMC

3-Chloromethcathinone (3-CMC) is a stimulant chemical compound that belongs to the substituted cathinone class. Substituted cathinones are synthetic derivatives of cathinone, a compound found in the khat plant. These substances are part of a larger group of psychoactive drugs known as phenethylamines. 3-CMC has been found in products marketed as research chemicals and is known for its stimulant effects, which can include increased energy, alertness, and euphoria. However, it also poses significant risks to health and has been associated with various adverse effects.

Chemistry[edit | edit source]

3-Chloromethcathinone is a structural analog of methcathinone, with a chlorine atom substituted at the 3 position of the phenyl ring. It is a chiral compound, and its molecular formula is C10H12ClNO. As a substituted cathinone, its structure is characterized by a phenethylamine core with an alkyl group attached at the alpha carbon and an oxygen group attached to the beta carbon. The presence of the chlorine atom in its structure influences its pharmacological properties and distinguishes it from other cathinones.

Pharmacology[edit | edit source]

The pharmacological action of 3-CMC is primarily as a central nervous system stimulant. It is believed to work by increasing the release of dopamine, norepinephrine, and serotonin in the brain, leading to its stimulant and euphoric effects. However, the exact mechanism of action is not fully understood, and research into its pharmacology is ongoing. Due to its structural similarity to other psychoactive substances, it is speculated that 3-CMC shares similar modes of action, including potential for abuse and addiction.

Effects[edit | edit source]

The effects of 3-CMC can vary depending on the dose, method of administration, and individual user characteristics. Common reported effects include:

  • Increased energy and alertness
  • Euphoria
  • Increased sociability
  • Enhanced sensory perception

However, 3-CMC use is also associated with a range of adverse effects, such as:

  • Tachycardia (rapid heartbeat)
  • Hypertension (high blood pressure)
  • Nausea and vomiting
  • Anxiety and paranoia
  • Potential for addiction and abuse

Legal Status[edit | edit source]

The legal status of 3-CMC varies by country, with some countries having specific legislation controlling its sale, distribution, and use. It has been classified as a controlled substance in several jurisdictions due to concerns about its potential for abuse, addiction, and harm to public health.

Safety and Toxicology[edit | edit source]

Limited information is available on the safety and toxicology of 3-CMC. Due to its status as a research chemical and the lack of comprehensive studies, the full extent of its health risks and toxic effects are not well understood. Users are advised to exercise caution and be aware of the legal and health risks associated with its use.

3-Chloromethcathinone Resources
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Contributors: Prab R. Tumpati, MD