3-methylcholanthrene

From WikiMD's Wellness Encyclopedia

3-Methylcholanthrene is a potent carcinogen and mutagen which is often used in scientific research to induce tumors in laboratory animals. It is a derivative of cholanthrene.

Chemical Structure[edit | edit source]

3-Methylcholanthrene is a polycyclic aromatic hydrocarbon (PAH) with the molecular formula C21H16. It has a complex structure with four fused rings, three of which are aromatic and one of which is a seven-membered ring. The methyl group is attached to one of the aromatic rings.

Uses in Research[edit | edit source]

In scientific research, 3-methylcholanthrene is often used to induce tumors in laboratory animals, particularly mice. It is also used in studies investigating the mechanisms of carcinogenesis and mutagenesis.

Health Effects[edit | edit source]

Exposure to 3-methylcholanthrene can have serious health effects. It is a potent carcinogen and mutagen, meaning it can cause cancer and genetic mutations. It is also toxic if swallowed, inhaled, or absorbed through the skin.

Safety[edit | edit source]

Due to its toxicity and carcinogenicity, 3-methylcholanthrene should be handled with extreme caution. It should be used only in a fume hood, and protective clothing, gloves, and eye/face protection should be worn at all times.

See Also[edit | edit source]

3-methylcholanthrene Resources
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Contributors: Prab R. Tumpati, MD