Alpha-Tocopherol palmitate

From WikiMD's Food, Medicine & Wellnesspedia

Alpha-Tocopherol Palmitate, also known as Vitamin E Acetate, is a synthetic derivative of Vitamin E used in dietary supplements, cosmetics, and some pharmaceutical preparations. It is a form of vitamin E that combines the antioxidant properties of tocopherol with palmitic acid, resulting in a compound that is more stable and has a longer shelf life than pure vitamin E.

Overview[edit | edit source]

Vitamin E is a group of eight fat-soluble compounds that include four tocopherols and four tocotrienols. Alpha-Tocopherol is the most active form of vitamin E in humans and is a powerful biological antioxidant. Antioxidants protect cells from the damaging effects of free radicals, which are molecules that contain an unshared electron. Free radicals can damage cells, and may contribute to the development of cardiovascular disease and cancer.

Alpha-Tocopherol Palmitate is created by esterifying alpha-tocopherol with palmitic acid. This process makes the vitamin E more stable against oxidation and extends its shelf life, making it a preferred form for cosmetic and pharmaceutical formulations.

Uses[edit | edit source]

Alpha-Tocopherol Palmitate is widely used in various industries due to its antioxidant properties, stability, and safety profile.

Dietary Supplements[edit | edit source]

In dietary supplements, Alpha-Tocopherol Palmitate serves as a source of vitamin E, contributing to the protection of cells from oxidative stress.

Cosmetics[edit | edit source]

In the cosmetic industry, it is used in skincare and beauty products to protect the skin from aging and environmental stressors. It also acts as a natural preservative, extending the shelf life of products.

Pharmaceuticals[edit | edit source]

Pharmaceutical formulations use Alpha-Tocopherol Palmitate for its antioxidant properties, which can help in the stabilization of drug products and in the protection of active pharmaceutical ingredients from oxidation.

Health Benefits[edit | edit source]

The health benefits of Alpha-Tocopherol Palmitate largely mirror those of vitamin E. These include:

  • Supporting immune function
  • Helping prevent the oxidation of LDL cholesterol, potentially reducing the risk of heart disease
  • Contributing to skin health by protecting it from oxidative damage and aging
  • Playing a role in eye health and possibly reducing the risk of age-related macular degeneration

Safety and Side Effects[edit | edit source]

Alpha-Tocopherol Palmitate is generally considered safe when used in recommended amounts. However, high doses of vitamin E can lead to nausea, diarrhea, stomach cramps, fatigue, weakness, headache, blurred vision, rash, and bruising and bleeding. People taking blood thinners or other medications should consult with a healthcare provider before taking vitamin E supplements.

Conclusion[edit | edit source]

Alpha-Tocopherol Palmitate is a valuable form of vitamin E with a wide range of applications in dietary supplements, cosmetics, and pharmaceuticals. Its antioxidant properties, stability, and safety profile make it an important ingredient in promoting health and protecting against oxidative damage.

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Contributors: Prab R. Tumpati, MD