Anti-dsDNA

Anti-dsDNA is a type of antibody that targets the DNA in the nucleus of cells. It is often associated with lupus, a chronic autoimmune disease.

Overview

Anti-dsDNA antibodies are a group of autoantibodies that target the DNA within cells. They are most commonly associated with lupus, a chronic autoimmune disease where the body's immune system mistakenly attacks healthy tissue.

Role in Lupus

In patients with lupus, the presence of anti-dsDNA is often a sign of disease activity. High levels of anti-dsDNA in the blood are often associated with severe lupus, particularly when kidney disease is present.

Testing for Anti-dsDNA

Testing for anti-dsDNA is a common part of diagnosing lupus. The test is often performed as part of a panel of tests that also includes antinuclear antibody (ANA) testing.

Treatment

Treatment for conditions associated with anti-dsDNA typically involves managing the underlying condition. In the case of lupus, this may involve medications to suppress the immune system and reduce inflammation.

See Also

• Systemic lupus erythematosus
• Autoantibody
• DNA
• Antinuclear antibody

Anti-dsDNA Resources
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