This category is for pandemic (from Greek πᾶν pan "all" and δῆμος demos "people"), an epidemic of infectious disease that has spread through human populations across a large region; for instance multiple continents, or even worldwide. Throughout history there have been a number of pandemics, such as smallpox and tuberculosis. More recent pandemics include the HIV pandemic as well as the 1918 and 2009H1N1 pandemics and COVID-19 in the COVID-19 pandemic.