Control event rate

Control event rate is a term used in clinical trials and epidemiology to refer to the rate at which a particular event, such as a disease or condition, occurs in a control group. The control event rate is used as a baseline to compare the effects of a treatment or intervention in a study group.

Definition

The control event rate (CER) is the proportion of patients in the control group of a randomized controlled trial (RCT) who experience the event or outcome of interest. It is used as a measure of the baseline risk of the event in the population being studied.

Calculation

The CER is calculated by dividing the number of events in the control group by the total number of participants in the control group. This gives a proportion, which can be expressed as a percentage.

Use in Clinical Trials

In clinical trials, the CER is used to compare the effectiveness of a new treatment or intervention against the standard treatment or no treatment. The difference between the CER and the event rate in the treatment group is known as the absolute risk reduction (ARR), which is a measure of the effectiveness of the new treatment.

Use in Epidemiology

In epidemiology, the CER is used to estimate the baseline risk of a disease or condition in a population. This can be used to calculate the relative risk (RR) and odds ratio (OR), which are measures of the association between an exposure and an outcome.

See Also

• Absolute risk reduction
• Relative risk
• Odds ratio
• Clinical trial
• Epidemiology

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