Crypt of Morgagni

Crypts of Morgagni are small, tubular structures found in the anatomy of the human body, specifically in the rectum. Named after the Italian anatomist Giovanni Battista Morgagni, these crypts are an integral part of the gastrointestinal tract and play a significant role in its function.

Anatomy

The Crypts of Morgagni are located in the lining of the rectum, where they form a series of small, tubular indentations. They are found between the anal columns, also known as the columns of Morgagni, which are vertical folds in the lining of the rectum. The crypts are lined with columnar epithelium, a type of tissue that is also found in various other parts of the body, including the stomach and intestines.

Function

The primary function of the Crypts of Morgagni is to secrete mucus. This mucus serves as a lubricant, facilitating the passage of feces through the rectum and out of the body. The crypts also play a role in the immune response of the gastrointestinal tract, as they contain lymphoid tissue that can respond to pathogens.

Clinical Significance

The Crypts of Morgagni can be involved in various medical conditions. For instance, they can become inflamed in a condition known as proctitis, which is inflammation of the rectum and anus. They can also be involved in the development of rectal cancer, as changes in the cells lining the crypts can lead to the formation of cancerous cells.

See Also

• Giovanni Battista Morgagni
• Rectum
• Anal columns
• Proctitis
• Rectal cancer