David Andrew Sinclair
David Andrew Sinclair, born in 1969, is a distinguished biologist and professor of genetics best known for his research on aging and life extension. Born in Australia, Sinclair currently serves at Harvard Medical School as a professor in the Department of Genetics.
Education and Early Career[edit | edit source]
Sinclair obtained his Bachelor of Science at the University of New South Wales, Sydney, and later earned his Ph.D. in Molecular Genetics. His Ph.D. research focused on the rapid aging disease known as Werner syndrome.
Research and Achievements[edit | edit source]
Sinclair's scientific work primarily revolves around understanding the biological mechanisms that underlie aging. He gained recognition for his studies on sirtuins, a class of proteins that contribute to cellular health, and their role in aging. His laboratory at Harvard Medical School has been instrumental in identifying and understanding the function of these proteins.
His work on resveratrol, a compound found in grapes and wine, has gained worldwide attention. He demonstrated that resveratrol can enhance the activity of sirtuins, thereby improving health and lifespan in various organisms.
Publications and Media Appearances[edit | edit source]
Sinclair has authored numerous scientific articles and is a co-journalist of the book "Lifespan: Why We Age and Why We Don't Have To." He has made several media appearances discussing his research and the potential of reversing aging.
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References[edit | edit source]
- "David Sinclair's Biography." Harvard Medical School. Link
- "The Sirtuin Story." National Institute on Aging. Harvard.edu
- Sinclair DA, Guarente L. "Unlocking the secrets of longevity genes." Scientific American. Scientificamerican.com
- Baur JA, Sinclair DA. "Therapeutic potential of resveratrol: the in vivo evidence." Nature Reviews Drug Discovery. Nature.com
- Sinclair DA. "Lifespan: Why We Age and Why We Don't Have To." Atria Books. Amazon.com
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