Etidronic acid

Etidronic acid (also known as 1-hydroxyethylidene-1,1-bisphosphonic acid or HEBP) is a bisphosphonate used in detergents, water treatment, cosmetics and pharmaceutical treatment. It is noted for its role in bone metabolism, specifically in the treatment of osteoporosis and Paget's disease.

Chemistry

Etidronic acid is a type of bisphosphonate, a class of drugs that bind to the hydroxyapatite found in bones. It has the chemical formula C2H8O7P2 and a molecular weight of 206.03 g/mol. The compound is a white crystalline powder that is soluble in water.

Uses

Detergents and Water Treatment

In detergents and water treatment, etidronic acid is used as a sequestering agent to bind and neutralize metal ions that would otherwise cause the water to be hard. This allows the detergent to foam more effectively and improves the effectiveness of the cleaning process.

Cosmetics

In cosmetics, etidronic acid is used as a stabilizer and to prevent the ingredients from separating. It is also used to control the pH of the product.

Pharmaceutical Treatment

In the pharmaceutical industry, etidronic acid is used in the treatment of bone diseases such as osteoporosis and Paget's disease. It works by slowing down the process of bone loss, helping to maintain bone density and reduce the risk of fractures.

Side Effects

Like all medications, etidronic acid can cause side effects. These can include gastrointestinal problems such as nausea, abdominal pain, and constipation, as well as more serious effects such as osteonecrosis of the jaw and atypical femoral fractures.

See Also

• Bisphosphonate
• Osteoporosis
• Paget's disease