Dimethoxymethamphetamine
Dimethoxymethamphetamine (also known as DOM, STP, or Serenity, Tranquility, and Peace) is a psychedelic drug and a member of the phenethylamine class. It is known for its potent psychoactive effects and has been used in both medical research and recreational contexts.
History[edit | edit source]
DOM was first synthesized and studied in the mid-1960s by Alexander Shulgin, a renowned chemist and psychopharmacologist. Shulgin's work on DOM and other psychedelic substances has been influential in the field of psychopharmacology.
Pharmacology[edit | edit source]
DOM acts as a potent partial agonist for the serotonin 5-HT2A receptor, leading to its psychedelic effects. It also has affinity for other serotonin receptors, contributing to its complex pharmacological profile.
Effects[edit | edit source]
The effects of DOM can vary widely depending on the dose, individual physiology, and set and setting. Common effects include visual hallucinations, altered thought processes, and heightened emotional sensitivity. Some users also report physical effects such as nausea, increased heart rate, and pupil dilation.
Risks[edit | edit source]
Like other psychedelic substances, DOM carries risks of psychological distress, particularly in individuals with a history of mental health issues. It can also cause physical side effects such as hypertension and tachycardia, particularly at high doses.
Legal status[edit | edit source]
DOM is a Schedule I controlled substance in the United States, meaning it is illegal to manufacture, distribute, or possess without a license. It is also controlled in many other countries under various drug laws.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD