Ethanolamine oleate
Ethanolamine Oleate is a sclerosing agent used in the treatment of esophageal varices. It is a type of ethanolamine salt of oleic acid and is often used in endoscopic sclerotherapy.
Chemical Structure[edit | edit source]
Ethanolamine Oleate is a long-chain fatty acid ester of ethanolamine. The oleate component is derived from oleic acid, a monounsaturated omega-9 fatty acid found in various animal and vegetable sources. The ethanolamine component is a primary amine and primary alcohol.
Pharmacology[edit | edit source]
Ethanolamine Oleate works by causing inflammation and fibrosis within the varices, leading to their obliteration. It is directly injected into the varices during an endoscopic procedure. The drug has a dual action: the ethanolamine causes sclerosis of the veins, while the oleate component induces thrombosis.
Clinical Use[edit | edit source]
Ethanolamine Oleate is primarily used in the treatment of esophageal varices, which are enlarged veins in the esophagus that can rupture and bleed. This condition is often associated with liver cirrhosis. The drug is also used in the treatment of gastric varices and hemorrhoids.
Side Effects[edit | edit source]
Common side effects of Ethanolamine Oleate include chest pain, fever, and difficulty swallowing. More serious side effects can include severe allergic reactions, blood clots, and perforation of the esophagus.
Contraindications[edit | edit source]
Ethanolamine Oleate should not be used in patients with known hypersensitivity to the drug. It is also contraindicated in patients with severe liver disease, as it can increase the risk of bleeding.
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD